Beta-Tricalcium Phosphate and Concentrated Growth Factors in Treatment of Intra-bony Defect Randomized Clinical Trial (RCT)
Malak
Shoukheba
Associate Prof of Oral Medicine, Periodontology, Oral Diagnosis and Oral Radiology, Faculty of Dentistry, Tanta University
author
Soheir
El Gholy
Lecture of Oral medicine, Periodontology, Oral Diagnosis and Oral Radiology, Faculty of Dentistry Tanta University
author
Sherouk
Gamal
Lecture of Oral Medicine, Periodontology, Oral Diagnosis, and Oral Radiology, Faculty of Dentistry Tanta University
author
text
article
2021
eng
This study was designed to assess the efficacy of biodegradable gelatin / Beta-tricalcium phosphate sponge socked in concentrated growth factors (CGF) in treating periodontal intra-bony defects, as compared with biodegradable gelatin /beta-tricalcium phosphate sponges alone. Materials and Methods: Twenty intra-bony defects ≥4 mm and pocket depth (PD) ≥5 mm in 20 patients were selected from the outpatient clinic of Oral Periodontology Clinic, Faculty of Dentistry, Tanta University to join in this study. Patients were randomly allocated into two groups 10 patients each. Group I was treated by surgery plus biodegradable gelatin /beta-tricalcium phosphate sponges, (control group). Group II was treated by gelatin/beta-tricalcium phosphate sponges socked in CGF. Bleeding on probing (BOP), PD, and clinical attachment level (CAL) were measured at baseline, 3, and 6months periods. Cone beam radiographs were taken at baseline, and 6 months after surgery evaluating the area of the defect (AD) and bone density (BD). Results: Both groups showed significant improvement in clinical parameters (P≤0.05). There were statistically significant differences in all investigated parameters between the two groups at 3 and 6 months in favor of group II, except for CAL there was no significant difference between them at 6 months. A significant decrease of DA and increase in BD at 6 months was noted for both groups with significant differences between them in favor of group II (P<0.05). Conclusion: Using a biodegradable gelatin/β-TCP socked in CGF could enhance the outcome of periodontal regeneration, as evidenced by improved bone density and reduction in the defect area.
Egyptian Dental Journal
The Egyptian Dental Association (EDA)
0070-9484
67
v.
4
no.
2021
3103
3112
https://edj.journals.ekb.eg/article_199292_f44b3948940b2ded29dcb76e2519d99b.pdf
dx.doi.org/10.21608/edj.2021.76474.1634
The Protective role of Nigella sativa versus Lepidium sativum on the submandibular salivary gland in hypercholesterolemic albino rat (Histological and Immunohistochemical study)
Enas
Hegazy
Assistant Professor, Oral Biology Department, Faculty of Dentistry, Suez Canal University
author
Tahany
Haggag
Assistant Professor, Oral Biology Department, Faculty of Dentistry, Cairo University
author
Merhan
Elmansy
Lecturer in Oral Pathology Department, Faculty of Dentistry, Suez Canal University
author
text
article
2021
eng
Abstract Background: Direct relation between hypercholesterolemia and hyposalivation was suggested. Phytosterols of herbal origin have been used as prophylactic or curative agents against many disorders. Objectives: Evaluate the protective role of Nigella sativa (Ns) versus Lepidium sativum (Ls) on the histological picture of submandibular salivary glands in hypercholesterolemic albino rat; and its immunomodulatory role of nuclear factor kappa B cell (NF-κB) and alpha smooth muscle actin (α-SMA) expression on the tissues. Materials and method: This study was performed with forty male albino rats, divided into four equal groups as follow: Group 1 (n=10): served as negative control, Group 2 (n=10): were fed with hypercholesteremic supplement (HCS) for 8 weeks. Group 3 (n=10): were fed HCS with oral administration of (Ns) seeds for 8 weeks. Group 4 (n=10): were fed HCS with oral administration of (Ls) seeds suspension for 8 weeks. Results: Histological results of submandibular salivary gland in group 2 revealed severe atrophic and degenerative changes in the secretory terminal portions & ducts. In group 3, the tissues appeared with nearly normal histological structures which reflect the beneficial effects of Ns. In group 4, a lesser degree of improvement was noticed with Ls. Quantitative analysis for α-SMA and NF-κB revealed highly statistically significant decrease in group 3 and 4 in comparison with group 2. Conclusion: The immunohistochemical finding confirmed the histological results of the present study that proved the superior protective effects of Ns rather than Ls seeds against hypercholesterolemia on the submandibular salivary glands of albino rats.
Egyptian Dental Journal
The Egyptian Dental Association (EDA)
0070-9484
67
v.
4
no.
2021
3113
3125
https://edj.journals.ekb.eg/article_199293_c7e9cece6dfe27c8c8bc4a9a736d6ce7.pdf
dx.doi.org/10.21608/edj.2021.77526.1649
Prevalence of oral white lesions in patients with end-stage renal disease: A Cross sectional study
Asmaa
Al Shafey
Assistant Lecturer at Department of Oral Medicine and Periodontology, Faculty of Dentistry, British University, Cairo,
Egypt. - Phd Candidate at Department of Oral medicine, Faculty of Dentistry, Ain Shams University, Cairo, Egypt.
author
Ashraf
Mahmoud
Head of Internal Medicine Department, Faculty of Medicine, Benha University, Cairo, Egypt
author
Amira
Abdel Azim
Associate Professor of Oral Medicine and Periodontology, Faculty of Dentistry, Cairo University, Egypt.
author
text
article
2021
eng
Introduction: End stage renal disease (ESRD) has accompanying oral pathologies that emerge from the disease process or from the impact of hemodialysis or both. Inevitably, untreated oral lesions may aggravate clinical presentation and prognosis of renal disease. The aim of our study was to investigate the clinical patterns of white lesions in the oral cavity in the patients having end-stage renal disease, and to study the factors associated with the appearance of these lesions. Methods: A cross-sectional, descriptive and observational study was designed to determine prevalence of oral white lesions among patients with ESRD attending the nephrology hemodialysis department for more than six months at Qalyub Hospital in Qalyub, Al Qalyubia Governorate, Egypt. A total of 114 adult participants of both genders from 30 up to 60 years were included in the study. A salivary pH and salivary flow rate were estimated. Results: Oral white lesions were found among 33 patients out of 114 with a prevalence of 28.9 % in the studied sample of ESRD patients. The most common oral white lesions were oral candidiasis (11.4%), Lichen planus or lichenoid reaction lesions (10.5%) and oral keratotic lesions (6.1%), while the least oral white lesions were Leukoplakia (2.6%) and uremic stomatitis (2.6%). Conclusion: An association between the prevalence of oral candidiasis and the following (salivary pH, salivary flow rate) was found. Also an association between uremic stomatitis and the higher blood urea and higher serum creatinine level was found in our studied sample of the patients with ESRD.
Egyptian Dental Journal
The Egyptian Dental Association (EDA)
0070-9484
67
v.
4
no.
2021
3127
3135
https://edj.journals.ekb.eg/article_199294_9b13b19d6572974847a53328ecc41265.pdf
dx.doi.org/10.21608/edj.2021.78968.1660
Pomegranate molasses and red grape vinegar: can they alleviate dysplastic changes in chemically induced oral squamous cell carcinoma in hamsters?
Samah
Ezzat
Lecturer of Oral Biology, Faculty of Dentistry, Mansoura University, Egypt
author
Amira
Elsherbini
Lecturer of Oral Biology, Faculty of Dentistry, Mansoura University, Egypt
author
Doaa
Esmaeil
Lecturer of Oral Pathology, Faculty of Dentistry, Mansoura University, Egypt
author
Mohamed
Abdulrahman
Associate professor of Oral Biology, Faculty of Dentistry, Mansoura University, Egypt
author
text
article
2021
eng
76 male hamsters were divided equally into 4 groups (19 each). Group I served as control group with no intervention. Group II received topical application of 0.5% 7, 12-dimethylbenz[a]anthracene (DMBA) on the left buccal pouches for 16week with no intervention. Group III received a 0.5ml of Pomegranate molasses plus 0.5 ml distilled water through ingestion daily concomitant with DMBA application and continued for 3 months post induction period. Group IV received a red grape vinegar in a protocol similar to group III. Then the pouches were collected fixed and processed for H&E, anti-TGF-β and anti-CK-19 staining. Results: group II showed classical dysplastic changes with statistically significant higher expression of anti-TGF-β and CK-19 (P<0.0001) compared to group III and IV. The later showed reduction of dysplastic changes and anti-TGF-β and CK-19 expression. There was no significant difference between the two treatment modalities. Conclusion: Both pomegranate molasses and red grape vinegar reduced the signs of dysplasia via reduction of TGF-β and CK-19 expression and consequently reduction of the EMT. Both pomegranate molassess and red grape vinegar represent a promising protective therapeutic modality for reduction of dysplastia and carcinogenesis.
Egyptian Dental Journal
The Egyptian Dental Association (EDA)
0070-9484
67
v.
4
no.
2021
3137
3146
https://edj.journals.ekb.eg/article_199295_cbe9e292ab14cfb55b4c426c1941a601.pdf
dx.doi.org/10.21608/edj.2021.79089.1662
TGF-β Paradox and the Progression of Osteoblastoma versus Osteosarcoma.
Maii
Sholqamy
Lecturer of Oral and Maxillofacial Pathology, Faculty of Oral and Dental Medicine, Minia University, Minia, Egypt.
author
text
article
2021
eng
Abstract Objective: To study the expression of Transforming Growth Factor beta-1 (TGF-β1) and Tumor protein 53 (Tp53) in osteoblastoma and osteosarcoma and the role of TGF-β paradox in the progression of these tumors. Materials and Methods: Twenty-two paraffin blocks were collected and classified into 7 blocks with classical osteoblastoma and 15 blocks with osteosarcoma. From each block, slide preparation for H&E and immunohistochemical staining by two markers: anti TGF-β1 antibody and anti Tp53 antibody were applied. Then we estimated the expression of each marker by ImageJ (version 1.41) and area fractions were measured. Results: Both classical osteoblastoma and osteosarcoma showed positive expression of TGF-β1. The expression of Tp53 was positive in osteosarcoma, but it was negative in osteoblastoma. Our statistical analysis revealed that the expression of TGF-β1 in osteosarcoma was stronger than in osteoblastoma but with no statistically significant difference. There was a significant moderate negative correlation between expression of the two markers in osteosarcoma. Conclusion: The mutual signaling is the main pillar in the progression of osteosarcoma and osteoblastoma. Interaction pathways between Tp53 and TGF-β1 may have a role in TGF-β paradox. Understanding this interaction may help in improving of the management and prognosis of osteosarcoma.
Egyptian Dental Journal
The Egyptian Dental Association (EDA)
0070-9484
67
v.
4
no.
2021
3147
3155
https://edj.journals.ekb.eg/article_199296_9fbcf343c09922fe6f1e81a741401e64.pdf
dx.doi.org/10.21608/edj.2021.79442.1665
Early Thymoquinone Injections and Expression of DNA Repair Enzymes in Hamster Buccal Pouch-Induced Dysplasia
Rania
Said
Associate Professor of Oral Pathology, Faculty of Dentistry, Suez Canal University, EGYPT
author
text
article
2021
eng
Because carcinogenesis is a multi-step process, Sporn (1976)suggested that the best time to control cancer is in its “preneoplastic” phase, before it has a chance to develop into “invasive” cancer. Therefore, the aim of the present work was to evaluate the effect of TQ on the dysplasia induced in that model, through IHC expression of both enzymes.6 weeks of DMBA painting resulted in irreversible genetic changes that did not resolve by the studied repair enzymes. So it can be proposed that TQ had resulted in regression of the carcinogenesis process through the following mechanisms. First: TQ as a potent antioxidant that antagonizes the adverse effect resulting from elevated ROS levels due to carcinogenesis i.e. reduction of the intracellular ROS allowed the repair enzymes to fulfill their main target.Second: TQ through inactivation of the TNF-Nf-κB pathway, and in turn induced p53 activation, i.e. stimulated apoptosis of malignant cells. Third: TQ has the ability to arrest cells at different phases of the cell cycle leading to growth inhibition, so allowing repair of mutated cells
Egyptian Dental Journal
The Egyptian Dental Association (EDA)
0070-9484
67
v.
4
no.
2021
3157
3169
https://edj.journals.ekb.eg/article_199297_568f19573af017503ac34b2d9e08a606.pdf
dx.doi.org/10.21608/edj.2021.81391.1679
Protective role of royal jelly to alleviate side effects of chemotherapy on submandibular salivary glands of albino rats (Histological and Electron Microscopic Study)
Nehad
Ahmad
Lecturer of Oral biology department Faculty of Dental Medicine for Girls AL-Azhar University
author
Noura
Bakr
Lecturer of Oral biology department Faculty of Dental Medicine for Girls AL-Azhar University.
author
text
article
2021
eng
Abstract Chemotherapeutic agent induces severe tissue injury. Royal jelly has beneficial biological effects. Aim: To evaluate the protective role of royal jelly on salivary glands of rats treated with cytarabine. Methods: 21 male albino rats were divided into three groups. Group I (control group) normal without any medication. Group II (cytarabine group) at dose 100mg/kg/ I.P. Group III (cytarabine & Royal jelly group) was administrated royal jelly prior to cytarabine injection. After 2weeks the submandibular glands were dissected and prepared for histological and electron microscopic (TEM) examinations. Results: Light microscopic examination of cytarabine group revealed deformity of the secretory portions with numerous intracellular vacuoles, deeply stained atrophied nuclei. Dilated excretory ducts with degenerated epithelial lining. Some secretory cells were degenerated. While Royal jelly treated group revealed well defined serous acini and well form striated ducts. TEM examination of cytarabine group revealed pyknotic nucli with nuclear polymorphism. Swollen mitochondria and dilated RER. Striated duct has ill-defined cell boundaries and cytoplasmic vacuolizations. These changes were improved at Royal jelly treated group. Conclusion: Administration of Royal jelly produced a protective effect against cytotoxic changes induced by chemotherapy in rat submandibular salivary glands.
Egyptian Dental Journal
The Egyptian Dental Association (EDA)
0070-9484
67
v.
4
no.
2021
3171
3180
https://edj.journals.ekb.eg/article_199298_de332d5d3b8c3f42dc25c250c3050e8b.pdf
dx.doi.org/10.21608/edj.2021.81813.1685
Survey on the occlussal morphology of the permanent maxillary molars in a sample of Egyptian Population
Ingy
Alsakhawy
Oral Biology, Faculty of Dentistry, Ain Shams University, Cairo, Egypt.
author
Marwa
Abd El Hameed
Assistant Professor, Oral Biology Dept, Faculty of Dentistry, Ain Shams University
author
Medhat
Elzainy
Professor, Oral Biology Dept, Faculty of Dentistry, Ain Shams University
author
text
article
2021
eng
Background:The study of dental morphological characteristics is useful for providing information for phylogenic, anthropological, forensic and genetic studies and understanding variations within and among species.The aim of the study was to investigate, compare and document the distinctive cuspal outlines and groove patterns of permanent maxillary molars in a sample of Egyptian population, this was performed morphologically through study casts inspection, followed by statistical analysis of the collected data. Materials and Methods: 50 upper study casts models of patients aged above 21 years from the Orthodontic Department of Faculty of Dentistry at Ain Shams University with all maxillary molars teeth present were collected. Results: Regarding cusp number and groove pattern of maxillary molars, M1 showed prevalence of 4H groove pattern while 3 cusps and U groove pattern was the most common pattern for M2&M3.Regarding the frequency of molar tubercle (tubercle of carabelli), M1 showed prevalence of type I molar tubercle(depression), while the absence of the molar tubercle was the most common pattern for M2 &M3.Occlusal outline of M1 showed prevalence of the rhomboidal outline while M3 showed prevalence of triangle outline. Statistical results showed significant difference between the maxillary molars.Conclusions: The morphological characteristics of teeth in a sample of Egyptian population were consistent with those of other studies performed on different populations using similar methodology.
Egyptian Dental Journal
The Egyptian Dental Association (EDA)
0070-9484
67
v.
4
no.
2021
3181
3192
https://edj.journals.ekb.eg/article_199299_f9d06af5943f678e97a9a44b61de96ec.pdf
dx.doi.org/10.21608/edj.2021.52596.1431
“HORIZONTAL ALVEOLAR RIDGE AUGMENTATION WITH AUTOGENOUS BLOCK BONE GRAFT A CONE BEAM COMPUTED TOMOGRAPHY EVALUATION CASE SERIES”
ALAA
ALI
Assistant Lecturer of Oral Medicine, Periodontology and Oral Diagnosis Faculty of Dentistry, Assiut University
author
Nevine
Kheir El Din
Professor of Oral Medicine, Periodontology and Oral diagnosis, Faculty of Dentistry, Ain shams University
author
AHMED
AMR
Assistant Professor of Oral Medicine, Periodontology and Oral Diagnosis, Faculty of Dentistry, Ain Shams
University
author
text
article
2021
eng
Objective: The aim of the present study was to evaluate horizontal alveolar ridge augmentation using autogenous block grafts harvested from mandibular symphysis without barrier membrane in severe maxillary anterior ridge defects. Materials and methods: Six healthy patients with horizontal defects of the maxillary alveolar ridges were selected for alveolar ridge augmentation (class IV atrophy according to Benic and Hammerle classification). These defects were treated by autogenous block onlay grafts harvested from mandibular symphysis protected by anorganic bovine bone particles only. bone width was assessed preoperative, immediately post-operative and after 6 months at re‐entry by cone beam computed tomography. Result: All block grafts sites provided sufficient ridge width for proper implant placement. Mean bone gain was 3.9mm. No soft tissue dehiscence occurred in any of the cases. Conclusion: A combination of autogenous block graft obtained from the symphysis, combined with particulates xenograft alone without barrier membrane is a predictable and successful technique for augmenting maxillary horizontal ridge deficiency.
Egyptian Dental Journal
The Egyptian Dental Association (EDA)
0070-9484
67
v.
4
no.
2021
3193
3202
https://edj.journals.ekb.eg/article_199464_bc73efa2125a44e900fa9278dd39a87a.pdf
dx.doi.org/10.21608/edj.2021.82900.1694
Root and Root Canal Morphology of Permanent Mandibular Anterior Teeth in a Sample of Egyptian Population
Hend
El-Messiry
Lecturer, Oral Biology, Faculty of Dentistry, Ain Shams University, Cairo, Egypt.
author
Marwa
Abd ElHameed
Associate Professor, Oral Biology, Faculty of Dentistry, Ain Shams University, Cairo, Egypt
author
text
article
2021
eng
Objectives The aim of this work was to study the morphology of root and root canals of permanent mandibular anterior teeth in a sample of the Egyptian population. Methods A total of 16 permanent mandibular central incisors (I1), 25 permanent mandibular lateral incisors (I2) and 15 permanent mandibular canines (C) were collected and classified into groups according to shape and number of roots. Molds of pink wax with the samples were submitted for cone beam computed tomography (CBCT). The number and shapes of roots were determined and types of root canals were assessed and classified according to Vertucci's classification. Finally, data was statistically analyzed. Results Regarding the macroscopic appearance of I1, all the samples had one root while I2 had one root with 92%. As for C, 80% of the sample was with one root. CBCT revealed the following configurations, according to Vertucci's classification; Regarding I1, Type I was the most common canal configuration (75%) followed by type II (12.5%) and type III (12.5%) Regarding I2, Type I (60%) was the most common configuration followed by type III (28%). As for C, 66.7% of the sample was represented by type I followed by type III and IV, where each was represented by 13.3%. Conclusions There are morphological variations in the root and root canal anatomies of the mandibular central incisors, lateral incisors, and canines of Egyptian population as compared to other populations.
Egyptian Dental Journal
The Egyptian Dental Association (EDA)
0070-9484
67
v.
4
no.
2021
3203
3209
https://edj.journals.ekb.eg/article_199465_22bbd1c16522ba981f6c288bc4e1c224.pdf
dx.doi.org/10.21608/edj.2021.85335.1713
Clinical evaluation of gingival margin stability following conventional versus microsurgical techniques of esthetic crown lengthening: a randomized controlled clinical trial.
Mohamed
Hassan
Master candidate at periodontology department faculty of dentistry, Cairo University
author
Manal
Hosny
Professor and head of department and of Oral Medicine and Periodontology, Faculty of Dentistry, Cairo University
author
Weam
Elbattawy
Ass. Prof. of Oral Medicine and Periodontology, Faculty of Dentistry, Cairo University
author
text
article
2021
eng
Aim: To assess the gingival margin stability following conventional versus microsurgical approach of esthetic crown lengthening in management of patients with anterior short clinical crowns. Methodology: Twenty-four patients indicated for esthetic crown lengthening were selected and divided into either test or control groups where microsurgical approach or conventional technique were performed respectively. All patients were assessed at different intervals (baseline, 3, and 6 months) for the outcomes: gingival margin (GM), Pink esthetic score (PES), soft tissue level (STL), mesial (MP) and distal papilla (DP) levels, postoperative swelling (POS), postoperative pain (POP) and patient satisfaction and were subjected to statistical analysis. Results: there was a statistically significant reduction in the gingival margin level after 3 and 6 months in both groups with statistically significant more mm and percentage reduction within the control group. The microsurgical approach showed a statistically significant improvement in the PES at 3 and 6 months, while the conventional approach showed a statistically significant improvement only at 6 months with no statistically significant percentage gain between both groups at 3 and 6 months. Less pain was experienced with the test group through less intake of analgesics. Also, less swelling was observed in the test group at day 2 and day 5 with statistically significant difference with more patient satisfaction. Conclusions: Both groups significantly improved all clinical outcomes after 6 months, but the microsurgical approach showed less postoperative pain, swelling and gained more patient satisfaction.
Egyptian Dental Journal
The Egyptian Dental Association (EDA)
0070-9484
67
v.
4
no.
2021
3211
3221
https://edj.journals.ekb.eg/article_199468_08a4cf662af29f1afe57a0ba587986ea.pdf
dx.doi.org/10.21608/edj.2021.86047.1714
PREVALENCE AND ANATOMICAL VARIATIONS IN THE MANDIBULAR LINGUAL CANAL IN A SAMPLE OF EGYPTIAN POPULATION USING CBCT: A CROSS-SECTIONAL STUDY
Orchidia
El-Hadidy
Master degree candidate Department of Oral and Maxillofacial Radiology, Faculty of Dentistry, Cairo University.
author
ahmed
hossam
Associate Professor, Department of Oral and Maxillofacial Radiology, Faculty of Dentistry, MSA University.
author
Ahmad
Abd El Samad
Associate Professor, Department of Oral and Maxillofacial Radiology, Faculty of Dentistry, Cairo University
author
Mushira
Dahaba
Professor of Oral and Maxillofacial Radiology, & Head of Quality Assurance Unit, Faculty of Dentistry, Cairo
University.
author
text
article
2021
eng
Aim: With the development of surgical procedures, as the mandibular anterior dental implants and chin surgeries, there has been an increase in complications associated with anatomical elements in this anterior area. One of the most dangerous complications is related to bleeding caused by injured vessels associated with the lingual foramen and canal, which can cause a compression of the airway. Methodology: Eighty-two CBCT scans for Egyptian individuals were collected from the data base available at the Department of Oral and Maxillofacial Radiology, Faculty of Dentistry, Cairo University. Scans were selected according to specific inclusion and exclusion criteria, they were interpreted by two oral radiologists and analyzed in the three planes axial, coronal and sagittal. The midline was drawn on the axial scan by a line passing through the convexity of the genial tubercle to the mental ridge. The procedure was then standardized by adjusting the slice thickness and the spacing between all cuts at 0.4mm. After determining the midline on the axial plane, from the sagittal plane five consecutive cuts were taken on each side of the midline, these cuts were used for the assessment of the prevalence and the number of lingual canals present.
Egyptian Dental Journal
The Egyptian Dental Association (EDA)
0070-9484
67
v.
4
no.
2021
3223
3229
https://edj.journals.ekb.eg/article_199473_ecd629fc7396c0d54e9598623c05c2af.pdf
dx.doi.org/10.21608/edj.2021.88504.1729
Effect of Different Voxel Sizes on Accuracy of 2D and 3D Mandibular Linear Measurements Using CRANEX® 3D Cone Beam Computed Tomography Machine: Preclinical Study
MOHAMED
SELIM
Oral radiology department, Faculty of dentistry, Cairo University, Cairo, Egypt
author
Mushira
Dahaba
Professor, Oral and Maxillofacial Radiology Department, Cairo university- Giza - Cairo
author
ahmed
Abdalsamad
Assistant Professor, Radiology Faculty of Dentistry Cairo University
author
text
article
2021
eng
Aim To assess the accuracy of linear measurement obtained from CBCT images in 3D volumetric rendering and multiplanar slices with different voxel sizes. Methodology: 9 mandibles with twelve radioopaque markers fixed on each one were imaged using CRANEX® 3D CBCT machine. Each mandible was imaged twice with voxel sizes 250 μm and 350 μm. 2D and 3D linear measurements from CBCT images were compared to the real physical measurements taken by a digital caliper. Software measurements were recorded twice by the principal investigator and once by the supervising professor. Intra- and inter-observer agreements were assessed using Intra-Class Correlation Coefficient (ICC). SPSS®IBM Version 24 and MedCalc® version 12.1 for Windows were used for statistical analysis. Results: CBCT 2D measurements with voxel sizes of 250μ and 350μ showed a mean difference= 0 mm both with 95% of difference being -0.6 mm above or 0.7mm below and-0.5 mm above or 0.6 mm below the Gold Standard respectively. CBCT 3D measurements with voxel sizes of 250μ and 350μ showed a mean difference= 0 mm both with 95% of difference being -0.5 mm below or 0.5 mm above and -0.6 mm above or 0.7 mm below the Gold Standard. Intra-observer and inter-observer reliability regarding all measurements showed excellent agreement. Conclusions: 2D and 3D measurements driven from CBCT images with voxel size of 350 μ are accurate as measurements driven from CBCT images with voxel size of 250 μ with less radiation delivered to the patient. 2D and 3D CBCT measurements driven from CBCT are reliable.
Egyptian Dental Journal
The Egyptian Dental Association (EDA)
0070-9484
67
v.
4
no.
2021
3231
3235
https://edj.journals.ekb.eg/article_199477_5bf7b6c2e889243bad5ac46cae4fa530.pdf
dx.doi.org/10.21608/edj.2021.89724.1739
Computer guided flapless versus Free hand flap surgery for implants supporting All-on-4 fixed prosthesis in atrophied mandible. One year clinical and radiographical results of a randomized trial.
Shaimaa
Nasr
Lecturer, Department of Oral Medicine and Periodontology, Fayoum University, Egypt
author
Ramy
Ali
Lecturer, Department of Removable Prosthodontics, Faculty of Dentistry, Fayoum University, Egypt.
author
text
article
2021
eng
Aim: The purpose of this study was to evaluate clinical and radiographical outcomes of computer guided flapless versus Free hand flap surgery for implants used to anchor All-on-4 fixed prosthesis in atrophied mandible. Materials and methods: Twelve completely edentulous patients with atrophied mandibular ridges were randomly assigned into two groups Group1 (Free hand flap surgery, control): received 4 implants using the All on four protocol and free hand flap surgery and metal guide. Group2 (computer guided flapless surgery, study): received 4 implants using computer guided flapless surgery and stereolithographic surgical guide. Implants were immediately loaded by acrylic prosthesis then full arch ceramometal fixed prosthesis was used as a final restoration. Plaque Index, Gingival Index, pocket depth, stability of the implants, and crestal bone loss were evaluated at baseline, 3, 6 and 12 months after loading. Results: The survival rate of the implants was 95.8% and 91.7% for group 1 and group 2. For both groups, implant stability significantly decreased from insertion to 3 months, and increased again at six months. For both techniques, crestal bone loss significantly increased with time. For all time intervals, flap group showed significant higher plaque index, gingival index, probing depth and crestal bone resorption than flapless group. Conclusion: Within the limits of this short-term randomized trial regarding the small sample size, computer guided flapless approach may be recommended for all on four implant rehabilitation of edentulous mandibles than conventional flap surgical approach as it was associated with favorable clinical and radiographical peri-implant parameters.
Egyptian Dental Journal
The Egyptian Dental Association (EDA)
0070-9484
67
v.
4
no.
2021
3237
3249
https://edj.journals.ekb.eg/article_199478_b365a86bee0da79e01ba2765f0c2a794.pdf
dx.doi.org/10.21608/edj.2021.90292.1747
The effect of Chronic Administration of Ampicillin/Sulbactum on rat Developing Enamel
ِِِAmr
Fatouh
Master Degree، Faculty of Ain Shams
author
dahlia
mohamed rateb
Assistant Professor of Oral Biology Faculty of Dentistry, Ain Shams University
author
Nuha
Abdullah Baraka
Lecturer of Oral Biology Faculty of Dentistry, Ain Shams University
author
text
article
2021
eng
Objective: This study aimed to evaluate the effect of chronic administration of Ampicillin/Sulbactum on enamel development of Albino rats’ mandibular first molar. Materials & Methods: Eight pregnant female Albino rats were equally divided into two groups: control and treated group. The treated group received intraperitoneal injection of 200 mg/kg BW of Ampicillin/Sulbactum once daily for nine days till delivery. This was followed by injection of the offspring for additional 11 days. Treated offsprings (n=7) were sacrificed at 12 day of birth and H&E stained sections of the mandibular first molar tooth germ were examined. The other half of the treated pups was sacrificed at 28 days of birth, their mandibular first molars were examined by quantitative computerized tomography (QCT), scanning electron microscope (SEM) & ground section then statistical analysis was performed for enamel measurements of H&E, ground sections and QCT Results: Examination of H&E stained sections of the Ampicillin/Sulbactam treated subgroup at 12 days revealed an apparent reduction in enamel matrix thickness which was statistically insignificant compared with control subgroup. QCT showed a significant decrease in enamel density of the treated subgroup compared with untreated subgroup at 28 days. SEM observation showed enamel surface irregularities, pores and fissures. An insignificant reduction in enamel thickness was revealed by statistical analysis of the ground sections under light microscope. Conculsion: Within the limitations of this study, chronic administration of Ampicillin/Sulbactam adversely affected the development of enamel in rat’s offspring.
Egyptian Dental Journal
The Egyptian Dental Association (EDA)
0070-9484
67
v.
4
no.
2021
3251
3258
https://edj.journals.ekb.eg/article_199479_d36de93ccdae6d43876df5ca83756fe9.pdf
dx.doi.org/10.21608/edj.2021.90100.1755
The effect of Erbium:YAG Laser for the Fibronectin Expression in Gingival Epithelium with Nifedipine induced Gingival Overgrowth
rasha
mostafa
Lecturer, Oral Medicine and Periodontology Department , Faculty of Dentistry Cairo University, Cairo, Egypt.
Oral Medicine and Periodontology Department, Faculty of Dentistry Badr University in Cairo, (BUC), Cairo, Egypt.
author
Marwa
Tawfiq
Lecturer, Oral medicine, Periodontology, and Diagnosis, Faculty of Oral and Dental Medicine Beni-Suef University.
author
text
article
2021
eng
Gingival overgrowth is one of the side- effects seen as a result of the regular administration of the calcium channel blocker anti-hypertensive drug Nifedipine. Fibronectin (FN), is an adhesive high molecular weight extra cellular matrix glycoprotein which plays an important role in influencing cell growth, adhesion, migration as well as extracellular matrix organization. It also contributes to fibroblast attachment and proliferation, and participates in the regulation of tissue fibrosis. Erbium: YAG laser was approved in 1997 by the U.S. Food and Drug Administration for hard and soft tissue treatment in dentistry. Several studies have been published to demonstrate its efficacy for bone cutting, plaque and subgingival calculus removal, as well as having an antiseptic effect on both soft and hard periodontal tissues. Conventional scaling in combination with Erbium: YAG laser has unexpectedly showed complete healing with (2 normalization of the gingiva, making further surgical treatment for gingival volume reduction unecessary.
Egyptian Dental Journal
The Egyptian Dental Association (EDA)
0070-9484
67
v.
4
no.
2021
3259
3269
https://edj.journals.ekb.eg/article_199480_264760688533c0d7bafeab6d003c0293.pdf
dx.doi.org/10.21608/edj.2021.88267.1754
Accuracy of linear measurements performed with two different software in cone-beam computed tomography scans of dry human mandibles
Walaa
Ahmed
Oral and Maxillofacial Radiology Faculty of dentistry Cairo university
author
text
article
2021
eng
Objectives: The present study aimed to assess the accuracy of linear measurements performed with two different CBCT software .(Romexis® software and ONDEMAND 3 D software). Methods: The sample consisted of 15 human mandibles marked with radiopaque markers of gutta-percha balls (size 80, 1.5 mm long) which were glued on the marked anatomical landmarks with cyanoacrylate gel, ten linear measurements were conducted on the dry mandibles using digital caliper to provide gold standard meaurments.The mandibles were scanned by using Planmeca ProMax 3D Mid and images exported into digital imaging and communication in medicine (DICOM) format to a DVD then imported in to two software programs.The same ten linear measurements were conducted on the scanned images by using measure length tool of both romexis and Ondemand software programs. Results: Intra-examiner reliability of gold standard and image measurements were found to be excellent, Inter-examiner reliability of physical and Romexis® software was found to be excellent (ICC>0.9) and the Inter-examiner reliability of physical and ONDEMAND 3 D software was found to be poor (ICC <0.5) Conclusions: Romexis® software is more reliable method for planning surgical procedure in the dental practice than ONDEMAND 3 D software. Keywords: Linear measurements, CBCT, dry mandible and software programs.
Egyptian Dental Journal
The Egyptian Dental Association (EDA)
0070-9484
67
v.
4
no.
2021
3271
3278
https://edj.journals.ekb.eg/article_199482_0cf33b9b8379e98f3f0b6b9df5a88c51.pdf
dx.doi.org/10.21608/edj.2021.93292.1773
Genetics and Oral Diseases: A Scoping Review
heba
fayed
Lecturer, Oral Surgery Department, Faculty of Dentistry, October 6 University.
author
Hala
Yassin
Professor of Oral Medicine & Periodontology Department, Faculty of Dentistry, October 6 University
author
soha
hassan
Associate Professor of Cell Biology, Basic Science Department, Faculty of Dentistry, October 6 University
author
waheed
mohamed
Lecturer, Oral Surgery Department, Faculty of Dentistry, October 6 University.
author
text
article
2021
eng
Introduction: Recently genes act as hereditary blueprints of humans in our modern evidence-based dentistry era, Genomic wide association studies (GWAS) have investigated genetic and environmental factors which are considered instruments in genesis of complex and wide range of oral & maxillofacial disorders and syndromes. Their findings indicated that genetic mutation & polymorphisms are involved in periodontal diseases and temporomandibular disorders (TMDs) etiology & play a role by contributing to small effects and in determining the course and outcome of these disorders. Oral tissues are unique in different aspects, but they share many genetic etiopathogenesis of various disorders that are common to tissues throughout the body. Conditions affecting oral and maxillofacial tissues may occur as a part of systemic conditions or syndromes or single gene mutation or multifactorial gene disorders or X-linked diseases. Objectives: This article provides scopic reviews on the previous and current human genetics factors association with oral, periodontal, and temporomandibular disorders, which may lead to revolutionized treatment and prevention plans in the future. Methods: The literature search was conducted through databases including Egyptian knowledge bank (EKB), and PubMed (NIH) by using scientific terms for periodontal disorders, oral diseases, TMDs and genetic mutation. Additional studies were identified by searching bibliographies of highly relevant articles.
Egyptian Dental Journal
The Egyptian Dental Association (EDA)
0070-9484
67
v.
4
no.
2021
3279
3289
https://edj.journals.ekb.eg/article_199481_6061dcbbf98edbd76e1b2727c2a98445.pdf
dx.doi.org/10.21608/edj.2021.91148.1757