The Egyptian Dental Association (EDA)
Egyptian Dental Journal
0070-9484
2090-2360
66
Issue 3 - July (Oral Medicine, X-Ray, Oral Biology & Oral Pathology)
2020
07
01
Evaluation of Salivary versus Serum Squamous Cell Carcinoma Antigen in Oral lichen Planus
1519
1525
EN
Maha
Abdelkawy
0000-0001-8771-4994
Lecturer of Oral Diagnosis, Oral Medicine, and Periodontology, Beni-Suef university, Egypt.
maha_abdelkawy@dent.bsu.edu.eg
Ahmed Nabil
Fahmi
Department of Oral Pathology, Faculty of Dentistry Beni-Suef university, Egypt
ahmednfahmi@dent.bsu.edu.eg
Olfat
Shaker
0000-0002-3031-3599
Department of Biochemistry, Faculty of Medicine, Cairo University
olfatshaker@yahoo.com
Shereen
Ali
0000-0003-3794-2491
Oral Medicine and Periodontology
Faculty of Oral and Dental Medicine
Cairo University
cherriesah@hotmail.com
10.21608/edj.2020.25690.1071
Background and Objectives: Oral Lichen Planus is a chronic, inflammatory, immune mediated disease affecting the oral cavity. It is the oral variant of the mucocutaneous disease lichen Planus. The pathogenesis of OLP has been deeply studied yet not totally clear, this prospective case control study aimed to evaluate squamous cell carcinoma antigen in serum and saliva of Oral lichen planus.<br /> Methods: 30 individuals were included in the study; oral lichen planus and healthy volunteers. Serum and salivary samples were collected from patients and volunteers. Pain score was performed using Visual Analogue Scale Thongprasom sign scoring for OLP was used to record the cases clinically; Oral lichen planus diagnosis was confirmed by histopathology. A double-antibody sandwich enzyme-linked immunosorbent assay was used to assay the level of Human squamous cell carcinoma antigen in samples.<br /> Results: Both SccAg in serum and saliva showed statistically significantly higher mean levels than control group. ROC curve analysis of the two markers showed 100 % diagnostic accuracy on differentiation from control group at cut-off values of 2.6 and 1.5 ng/ml for Scc Ag in serum and saliva, respectively.<br /> Conclusion: Salivary SccAg can be considered as a significant diagnostic test for OLP disease activity.
Squamous Cell Carcinoma Antigen,Oral lichen planus,biomarker,Salivary biomarkers
https://edj.journals.ekb.eg/article_102992.html
https://edj.journals.ekb.eg/article_102992_d4bfa202823665fb7ae296fccf49ec0f.pdf
The Egyptian Dental Association (EDA)
Egyptian Dental Journal
0070-9484
2090-2360
66
Issue 3 - July (Oral Medicine, X-Ray, Oral Biology & Oral Pathology)
2020
07
01
Three-Dimensional Image Segmentation of Upper Airway by Cone Beam CT: A Review of Literature
1527
1535
EN
Sara
El Khateeb
0000-0002-1570-4524
Oral Medicine, Periodontolgy, Diagnosis and Oral Radiology, Faculty of Dentistry, Ain Shams University, Cairo, Egypt.
Department of Basic Dental Sciences, College of Dentistry, Princess Nourah bint Abdurahman University, Riyadh, KSA.
saraelkhateeb77@gmail.com
10.21608/edj.2020.25972.1074
The aim of this paper is to review the different approaches of three-dimensional image segmentation using cone-beam computed tomography (CBCT), with a focus on the human upper airway. Literature reviews in the dental field have been included, relating to the use of CBCT to assess the upper airway using image segmentation.<br /> <br /> Obstruction of the upper airway often modifies normal breathing, which can have a noticeable impact on the typical development of craniofacial structures. CBCT is a modality that allows for the improved understanding of airway anatomy, pathology, and upper airway analysis. It is more accurate, efficient and has a relatively less radiation dose compared to multi-detector CT. <br /> <br /> Three-dimensional (3D) models of the upper airway that have been segmented and designed from CBCT images can be used to visualize and analyze treatment efficiency in subjects with breathing or obstruction disorders. The accuracy of these 3D morpho-functional analytical models is essential for improving diagnosis, treatment planning, and assessing treatment outcomes of the upper airway. <br /> <br /> Therefore, the purpose of the present review is to discuss the different methods for upper airway segmentation using CBCT to achieve accurate modeling.
upper airway,Image,segmentation,cone beam CT,three-dimensional
https://edj.journals.ekb.eg/article_102993.html
https://edj.journals.ekb.eg/article_102993_f7101cae8cd8943dbbd0992a8813acf2.pdf
The Egyptian Dental Association (EDA)
Egyptian Dental Journal
0070-9484
2090-2360
66
Issue 3 - July (Oral Medicine, X-Ray, Oral Biology & Oral Pathology)
2020
07
01
Effectiveness of Topical Hyaluronic Acid Versus Chlorhexidine Mouthwashes in The Treatment of Recurrent Aphthous Stomatitis: A Randomized Clinical Trial
1537
1543
EN
Mai
Zakaria
0000-0002-2846-6094
Oral Medicine & Periodontology Department, Faculty of Dentistry, Cairo University, Egypt.
mai.zakaria@dentistry.cu.edu.eg
Amira
Abdelwhab
0000000306804555
Oral Medicine Department, Faculty of Dentistry, October 6th University, Egypt.
amira.abdelwhab.dent@o6u.edu.eg
Sandy
Hassan
0000-0001-8878-0002
Oral Medicine & Periodontology Department, Faculty of Dentistry, Fayoum University, Egypt
shs111@fayoum.edu.eg
10.21608/edj.2020.26938.1092
Abstract<br /> Background: Recurrent aphthous stomatitis (RAS) is the most common disorder affecting oral mucosa. The present study was designed to assess the clinical effectiveness of utilizing topical hyaluronic acid (HA) against chlorhexidine (CHX) mouthwashes as a control in RAS treatment. <br /> Materials and methods: Thirty-four patients with minor RAS were included in the trial. They were equally allocated into two groups with random distribution to rinse with CHX mouthwash as a control (Group I, CHX Group) and HA mouthwash in (Group II, HA group) as a study group. Evaluation of pain intensity and ulcer size were done in all study patients at baseline, 3 days and 7 days observational times. Duration of healing period was assessed in both study groups.<br /> Results: The results demonstrated a significant lowering in pain score and ulcer size in each group. Lower mean values of these outcomes were recorded in HA group compared to CHX group at 3 days and 7 days with significant difference regarding pain score. Concerning the duration of healing a significant decrease was recorded in HA group compared to CHX group. <br /> Conclusion: In conclusion, topical HA is a safe and effective treatment option for RAS with better pain control and healing duration.
Recurrent aphthous stomatitis,chlorhexidine,Hyaluronic acid,Healing,Pain
https://edj.journals.ekb.eg/article_103027.html
https://edj.journals.ekb.eg/article_103027_e60fd8e3d10c89cba752e6206a226007.pdf
The Egyptian Dental Association (EDA)
Egyptian Dental Journal
0070-9484
2090-2360
66
Issue 3 - July (Oral Medicine, X-Ray, Oral Biology & Oral Pathology)
2020
07
01
Syndecan-1, CD117 and CD56 Immunohistochemical Evaluation of Plasmacytoma
1545
1552
EN
hanan
eid
gamal
Oral and Maxillofacial Pathology, faculty of oral and dental medicine, Minia University, Minia, Egypt.
hanan.eid@mu.edu.eg
Sherif
Faroq
Elgayar
0000-0002-7725-3722
Oral and Maxillofacial Pathology, faculty of oral and dental medicine, Minia University, Minia, Egypt.
selgayar@gmail.com
Maii
Ibrahim
Sholqamy
0000000278208261
Oral and Maxillofacial Pathology, faculty of oral and dental medicine, Minia University, Minia, Egypt.
maii.sholqamy@yahoo.com
10.21608/edj.2020.27226.1096
Background and Objective: World Health Organization (WHO) describes two types of plasmacytomas which are solitary bone plasmacytoma (SBP) and extramedullary plasmacytoma (EMP). 17% to 33% of plasmacytomas, will progress into multiple myeloma (MM). The early diagnosis is very important as the plasmacytoma may be primary or metastatic lesion of MM. Prognosis of solitary plasmacytoma could be worse if it recurred as in case of its evolution toward systemic MM. Methodology: 10 patients with plasmacytoma in the National Cancer Institute and Histopathological laboratory of Minia University were analyzed immunohistochemically for detection of syndecan-1 as a diagnostic marker for plasmacytoma and detection of plasmacytoma behavior through interpretation the expression of both CD117 and CD56. Results: All cases showed strong positive immunoreaction for Syndecan-1(grade 3) according to scoring system for immunohistochemical expression. The expression of CD117 in plasmacytoma was similar to the expression of CD56, (60%) showed grade 1, while (40%) were grade 0. Conclusion: We concluded that the importance of histopathological biopsy for early diagnosis and prognostic evaluations are important in that the plasmacytoma may be a primary or metastatic lesion of MM. and Syndecan-1can be used as diagnostic marker for plasma cells, while CD56 and CD117 expressed only in neoplastic plasma cells and their expression indicate good prognosis.
plasmacytoma,syndecan 1,CD117,CD56,Immunohistochemistry
https://edj.journals.ekb.eg/article_102994.html
https://edj.journals.ekb.eg/article_102994_1398063deca56ae4cf8c1b80799997f3.pdf
The Egyptian Dental Association (EDA)
Egyptian Dental Journal
0070-9484
2090-2360
66
Issue 3 - July (Oral Medicine, X-Ray, Oral Biology & Oral Pathology)
2020
07
01
CBCT Assessment of Pneumatization of the Articular Tubercle and the Roof of the Glenoid Fossa: a retrospective study
1553
1562
EN
Dina
ElBeshlawy
0000-0002-0358-828X
Oral and Maxillofacial Radiology, Faculty of dentistry, Cairo University
dina.elbeshlawy@dentistry.cu.edu.eg
10.21608/edj.2020.27346.1098
Objectives: To determine the prevalence of the pneumatization of the articular tubercle (PAT) and glenoid fossa (PGF) concerning the sex, laterality and locularity in a sample of Egyptian population using CBCT images.<br /> Subjects and methods: 210 CBCT scans (74 males and 136 females) were assessed retrospectively by an oral and maxillofacial radiologist. The presence of pneumatization was identified bilaterally on a serial of reformatted sagittal cuts at the articular tubercle and the roof of the glenoid fossa. Age and sex for all patients were recorded as well as the type and laterality for the pneumatization cases.<br /> Results: 19.1 % of the scans exhibited PAT and 35.24% exhibited PGF. Of the scans found with PAT, 50% were unilateral (20% on the right and 30% on the left) and 50% were bilateral. Moreover, 15 of the PAT cases were unilocular and 28 were multilocular with 3 cases showing different locularity between sides. For PGF, 41.9% of the PGF cases were unilateral (13.5% on the right and 28.4% on the left) and 58.1% were bilateral. Only 16 of the PGF cases were unilocular, while 61 were multilocular with 3 cases also showing different locularity between sides. There was no significant difference between both sexes regarding the PAT or PGF prevalence, laterality or locularity.<br /> Conclusion: In the studied sample, the prevalence of PAT and PGF was 19.1 and 35.24% respectively. The prevalence was not linked to sex or laterality or locularity.
CBCT,articular tubercle,glenoid fossa,pneumatization
https://edj.journals.ekb.eg/article_102996.html
https://edj.journals.ekb.eg/article_102996_074eb3c96468e63e6325a94eb44984eb.pdf
The Egyptian Dental Association (EDA)
Egyptian Dental Journal
0070-9484
2090-2360
66
Issue 3 - July (Oral Medicine, X-Ray, Oral Biology & Oral Pathology)
2020
07
01
The Association Between Expression of Ki-67 and MMP-7 proteins and Lymph Node Metastasis in Malignant Salivary Gland Tumors
1563
1569
EN
Enas
Alaa Eldin
Abd El-Aziz
0000-0002-1658-6304
Oral and Maxillofacial Pathology Department, Faculty of dentistry, Minia University, Minia, Egypt
enasalaaeldin@yahoo.com
10.21608/edj.2020.27386.1099
Aim of the work: To analyze the expression of both Ki-67 and MMP-7 proteins in malignant salivary gland tumors by immunohistochemistery and correlate the results with lymph node metastasis and some clinical parameters including sex, site and type of the tumor.<br /> Material and Methods: The study was retrospectively designed. Thirty formalin fixed paraffin embedded blocks of different malignant salivary gland tumors were stained immunohistochemically for both Ki-67 and MMP-7. Immunostainig was evaluated and results were analyzed statistically in relation to lymph node metastasis and some clinical parameters as sex, site and type of the tumor. P Value ≤ 0.05 was considered significant.<br /> Results: High Ki-67 (P=0.0001) and MMP-7 expression (P=0.0001) was associated with lymph node metastasis. Ki-67 and MMP-7 immunostaining was not affected by either sex or site of the tumor but there was high association with type of the tumor.<br /> Conclusion: MMPs and Ki-67 may have prognostic impact in malignant salivary gland tumors and can be used in molecular targeted therapy.
Ki-67,MMP-7,salivary gland tumors
https://edj.journals.ekb.eg/article_102998.html
https://edj.journals.ekb.eg/article_102998_e50b7dbf39f4e84db5ea1dd86d733e6d.pdf
The Egyptian Dental Association (EDA)
Egyptian Dental Journal
0070-9484
2090-2360
66
Issue 3 - July (Oral Medicine, X-Ray, Oral Biology & Oral Pathology)
2020
07
01
The Carcinogenic Potential of Cadmium in Gingival Epithelium of Rats (Histological and Immunohistochemical Study)
1571
1577
EN
Laila
Amin
0000-0002-2357-0810
Oral Biology Department, Faculty of Dentistry, Mansoura University
Oral Biology Department, Faculty of Dentistry, Horus University, New Damitta
lailalsyd@yahoo.com
Mahmoud
Elsherbeny
Oral Pathology Department, Faculty of Dentistry, Mansoura University
dr.mahmoudasnan@yahoo.com
Mazen
Abou Elkhier
Oral Biology Department, Faculty of Dentistry, Mansoura University
mazenae_2000@yahoo.com
10.21608/edj.2020.27523.1101
Cadmium is a toxic, heavy industrial metal that causes serious environmental health hazards. Cadmium containing compounds have been classified as known human carcinogens and epidemiological data show causal associations to different types of cancers. This study designed to assess the carcinogenic effects of Cadmium on the gingival tissue of rats. Material and methods; Sixteen male albino Rats (age: 8 to 10 weeks and about 150 to 180 g body weight) from Animal Center of Faculty of Medicine, Mansoura University. The animals were divided into two equal groups, group I (control) and group II (cadmium chloride) rats were given 2 ml dose of a solution containing 10 mg/kg body weight of monohydrated cadmium chloride orally by gavage needle for 24 days. By the end of experiments, gingival epithelium around the teeth were carefully dissected, processed and stained using Haematoxyline & Eosin and immunohistochemical evaluation by iNOS. Statistical analysis was done to observe the statistical significant differences between the Cd group and control group in relation to dysplastic changes and iNOS immunoreaction. Results: the gingival tissue of Cd group revealed several dysplastic changes as, drop shape rete pegs, loss of polarity of basal cells, nuclear hyperchromatism, pleomorphism and increased mitotic pattern. a statistical significant difference regarding iNOS immunoreaction was found between control group and Cd group. conclusion to this study Cadmium chloride at low concentration and longtime of exposure can cause dysplastic changes in gingival tissue of rats.
Cadmium chloride,Carcinogenic,Gingiva,Hyperplasia,iNO
https://edj.journals.ekb.eg/article_103031.html
https://edj.journals.ekb.eg/article_103031_7d42bd9891107d2435a7ad8ce8e6ffe3.pdf
The Egyptian Dental Association (EDA)
Egyptian Dental Journal
0070-9484
2090-2360
66
Issue 3 - July (Oral Medicine, X-Ray, Oral Biology & Oral Pathology)
2020
07
01
Evaluation of the Effect of Matrine on Human Laryngeal Squamous Cell Carcinoma Cell Line
1579
1585
EN
Enas
Alaa El-Din
Abd El-Aziz
0000-0002-1658-6304
Oral and Maxillofacial Pathology Department, Faculty of dentistry, Minia University, Minia, Egypt
enasalaaeldin@yahoo.com
10.21608/edj.2020.27806.1102
Aim of study: to evaluate the possible anticancer potential of Matrine, one of the main active components extracted from dry roots of Sophora flavescens Ait (Leguminosae), on human laryngeal squamous cell carcinoma cell line (Hep-2).<br /> Material and methods: Prepared (Hep-2) cell line was treated with different concentrations of Matrine for 48 hours. The effect of Matrine on cell line was investigated using MTT assay, cytological examination and nuclear morphometric analysis of treated cells to explore the effect of the drug on cell proliferation and induction of apoptosis. The results were analyzed statistically. P value ≤ 0.05 was considered significant.<br /> Results: MTT assay showed that the proliferation of Matrine treated cells (in relation to control cells) decreased in a dose dependent manner. Morphometric analysis showed a decrease in nuclear area factor (NAF), which is an indicator of apoptosis, as concentrations increased. The results were statistically significant.<br /> Conclusion: Matrine has a cytotoxic effect on Hep-2 cell line through induction of apoptosis.
Matrine,apoptosis,laryngeal carcinoma
https://edj.journals.ekb.eg/article_103032.html
https://edj.journals.ekb.eg/article_103032_3e7546c7181873e5bec0c9271997ef32.pdf
The Egyptian Dental Association (EDA)
Egyptian Dental Journal
0070-9484
2090-2360
66
Issue 3 - July (Oral Medicine, X-Ray, Oral Biology & Oral Pathology)
2020
07
01
Platelet Rich Fibrin Versus Hyaluronic Acid as palatal wound Dressings following epithelialized free gingival graft harvest: A randomized controlled clinical trial
1587
1597
EN
Ahmed
Hassan
Associate Professor of Oral Medicine, Periodontology and Diagnosis, Faculty of Dentistry, Ain Shams University
ahmed72@asfd.asu.edu.eg
Nourhan
Akl
BDS Faculty of Dentistry Misr International University, MSc Periodontology Department Ain Shams University
nourhan8976@gmail.com
Doaa
Adel-Khattab
0000-0002-0254-0890
Lecturer of Oral Medicine, Periodontology and Diagnosis, Faculty of Dentistry, Ain Shams University
dr.doaa.adel-khattab@dent.asu.edu.eg
10.21608/edj.2020.31768.1136
Introduction: Patient centered outcome became of great interest nowadays. Patient’s pain and discomfort following free gingival graft procedure are common complain. Different palatal dressings are suggested to cover and protect the palatal donor site as stents, collagen gelatin scaffolds, platelet rich fibrin (PRF), hyaluronic acid (HA) and Alvogyl. However, in the literature no ideal agent has been emphasized.<br /> <br /> Objectives: This randomized controlled clinical trial compares for the first-time the effect of PRF versus HA palatal wound dressings on postoperative pain, post-surgical bleeding, and wound healing.<br /> <br /> Materials and methods: Following sample size calculation, 30 systemically healthy patients requiring palatal mucosal graft harvesting were randomized to receive either PRF or HA (intervention groups) or gelatin sponge (control group) as palatal dressings. Patient-reported visual analogue score (VAS) pain scores as primary outcome. Post-surgical bleeding and wound healing were considered as secondary outcomes.<br /> <br /> Results: VAS pain scores were reported minimal in PRF group throughout follow up intervals, PRF was statistically significant when compared to HA group at 3 and 7 days postoperative, PRF was statistically significant when compared to control group from 3 to 30 days postoperative and VAS in PRF was nearly 0 in day 14. PRF group showed the highest value of healing index during all the follow up intervals with mean 4.4 at 30 days that indicates a full healing of palatal wound area.<br /> <br /> Conclusions: Within this study’s limitations, PRF had better outcomes than both HA and gelatin sponge in means of cost, pain reduction, hemostasis and healing properties.
Platelets rich fibrin,Hyaluronic acid,palatal dressing
https://edj.journals.ekb.eg/article_103033.html
https://edj.journals.ekb.eg/article_103033_6ad1c60b492f03f1a46cda5e03cc2198.pdf
The Egyptian Dental Association (EDA)
Egyptian Dental Journal
0070-9484
2090-2360
66
Issue 3 - July (Oral Medicine, X-Ray, Oral Biology & Oral Pathology)
2020
07
01
Modulatory Role of Melatonin on the Structure of Hard Palatal Mucosa of Aged Rats
1599
1610
EN
Rania
Ahmed
Awwad
0000-0002-9982-8689
Oral Biology dep., Faculty of Dentistry, Ain Shams University, Cairo, Egypt.
rania.a.awwad@dent.asu.edu.eg
10.21608/edj.2020.33107.1149
Introduction: Aging greatly diminishes the ability of oral tissues to withstand various types of functional insults, and reduces cell regeneration. Hence, anti-oxidation is mandatory to preserve oral tissues especially while aging. Melatonin is an anti-oxidant with established potential in hindering age-related changes. Aim: to evaluate the extent of anti-oxidant and anti-inflammatory potentials of melatonin on aged hard palatal tissues of rats. Materials & Methods: twenty-one Albino rats 200-250 gms each, were used in this study. They were equally divided into 3 groups; Control Young Gp: 6 months of age, Control Senile Gp:18 months of age, and Melatonin Gp: 18 months of age. After 8 weeks, rats were sacrificed by high dose of anesthesia. The hard-palatal mucosae of all rats were separated and processed for histologic examination by H&E, Masson Trichrome stain, and immuno-histochemical staining by Anti-PCNA, then examined by light microscopy. Results: the control senile Gp showed statistically significant increase in vacuolated epithelial cells and area percentage of mature collagen fibers, as well as statistically significant reduction in PCNA-positive cells and apparent reduction of epithelial thickness. On the other hand, the melatonin Gp displayed statistically significant increase in PCNA-positive cells, area percentage of immature collagen fibers, while significant decrease in No. of vacuolated epithelial cells and apparent increase of epithelial thickness.<br /> Discussion: Aging resulted in deteriorated regeneration, enhanced apoptosis, with reduced cellularity and vascularity. On the other hand, melatonin greatly improved cellular proliferation, reduced apoptosis, enhanced CT tissue regeneration and collagen production. As well as reduction in inflammatory cells.
aging,Hard Palatal Mucosa,Melatonin
https://edj.journals.ekb.eg/article_103034.html
https://edj.journals.ekb.eg/article_103034_4b39ba1ea850bd36c22f3ff561219f35.pdf
The Egyptian Dental Association (EDA)
Egyptian Dental Journal
0070-9484
2090-2360
66
Issue 3 - July (Oral Medicine, X-Ray, Oral Biology & Oral Pathology)
2020
07
01
The Efficacy of Squamous Cell Carcinoma Antigen in the Differential Diagnosis of Oral squamous Cell Carcinoma.
1611
1617
EN
Maha
Abdelkawy
0000-0001-8771-4994
Lecturer of Oral Diagnosis, Oral Medicine, and Periodontology, Beni-Suef university, Egypt.
maha_abdelkawy@dent.bsu.edu.eg
Shereen
Ali
0000-0003-3794-2491
Oral Medicine and Periodontology
Faculty of Oral and Dental Medicine
Cairo University
cherriesah@hotmail.com
Ahmed Nabil
Fahmi
Department of Oral Pathology, Faculty of Dentistry Beni-Suef university, Egypt
ahmednfahmi@dent.bsu.edu.eg
Olfat
Shaker
0000-0002-3031-3599
Department of Biochemistry, Faculty of Medicine, Cairo University
olfatshaker@yahoo.com
10.21608/edj.2020.33181.1150
Abstract <br /> Background and Objectives: <br /> Oral squamous cell carcinoma (OSCC) is a major oral cancer representative. Squamous cell carcinoma antigen (Scc-AG) is detected in squamous cell carcinoma of oral tissues and other different tissues. Oral lichen planus (OLP) is a chronic inflammatory disease with questionable malignant transformation. <br /> Methods:<br /> Forty-five participants divided into OSCC group and two control groups: oral lichen planus as an inflammatory disease (positive control) and healthy volunteers (negative control). Clinical staging and grading of OSCC was recorded. A double-antibody sandwich enzyme-linked immunosorbent assay was used to evaluate the level of Scc-AG in serum and saliva.<br /> Results:<br /> Statistically significant difference for serum and salivary Scc-Ag, was found between the groups; OSCC, OLP on one hand and healthy controls on the other hand. No statistically significant difference was found between OSCC and OLP control groups in serum levels, while for salivary Scc-Ag a statistically significant difference was found between these two groups, with the higher values in OLP. Staging and grading in OSCC group were not found to be related to Scc-Ag level.<br /> Conclusion:<br /> Serum Scc-Ag cannot be used as a biomarker to differentiate between oral malignant and chronic inflammatory lesions. On the other hand, salivary Scc-Ag determination provides results more reliable than serum Scc-Ag and could be used in monitoring inflammatory oral disease activity as well as malignant conditions and could differentiate between them.
Squamous Cell Carcinoma Antigen,biomarker,Oral squamous cell carcinoma,Oral lichen planus,Salivary biomarkers
https://edj.journals.ekb.eg/article_103035.html
https://edj.journals.ekb.eg/article_103035_3c8b294e2206afe9236ee5dabf6a8ab1.pdf
The Egyptian Dental Association (EDA)
Egyptian Dental Journal
0070-9484
2090-2360
66
Issue 3 - July (Oral Medicine, X-Ray, Oral Biology & Oral Pathology)
2020
07
01
COMPARISON OF THE EFFECT OF DIFFERENT IMPLANT CONNECTIONS ON STRESS DISTRIBUTION AROUND DENTAL IMPLANTS (IN VITRO STUDY)
1619
1626
EN
Moustafa
Soliman
BDS Faculty of Dentistry Alexandria University, MSc periodontology department ain shams university
moustafa.soliman89@gmail.com
Nevine
Hassan
Kheir El Din
0000-0001-8472-6295
Professor of Oral Medicine, Periodontology and Oral diagnosis, Faculty of Dentistry, Ain shams University
kheireldinnevine@yahoo.com
Mohamed
Wagdy
Bissar
0000-0001-9051-5902
Lecturer of Oral Medicine, Periodontology and Oral Diagnosis, Faculty of Dentistry, Ain Shams University
mohamedbissar_1@yahoo.com
10.21608/edj.2020.26365.1088
INTRODUCTION: In implant dentistry literature, the commonly used materials in FEA studies can be classified as either implant, peri-implant bone (cortical and cancellous bone), and restoration. This method allows application of simulated forces at specific points in the system and stress analysis in the peri-implant region and surrounding structures. The implant connection system and other factors as the prosthesis type, length and material of restoration have a great effect on stresses falling on the bone around implant<br /> OBJECTIVES: was to evaluate and calculate the stress distribution with finite element analysis between implant in optimum apicocoronal position and implant in 6 mm vertical defect as well as between Internal Hex and Morse Taper connections.<br /> MATERIAL AND METHODS: In this study the stresses falling on surrounding bone, abutment, fixture and screw were analyzed in the two different configurations. In the first configuration, the jawbone has no defects. It is composed starting from the top of the bone, of 1 mm layer of crestal cortical bone, 3.5 mm layer of cancellous bone, 0.5 mm sinus cortical bone and a bottom layer of graft bone. In the second configuration, a vertical bone defect was created. The implants examined throughout this study were titanium implant with Morse taper and internal hex connections.
Morse,Hex,Defect,Stress
https://edj.journals.ekb.eg/article_103398.html
https://edj.journals.ekb.eg/article_103398_8cdf9226141c60a21367d2b06628ff4d.pdf