EVALUATION OF BONE REGENERATION OF MAXILLARY CYSTIC DEFECT GRAFTED WITH PUERARIN WITH CALCIUM SULPHATE GRANULES VERSUS CALCIUM SULPHATE GRANULES AS A SOLOGRAFT: A RANDOMIZED CONTROLLED CLINICAL TRIAL

Document Type : Original Article

Authors

Associate Professor Oral Surgery Department, Faculty of Dentistry, Cairo University, Egypt

Abstract

Aim: The aim of this study was to evaluate bone regeneration of maxillary cystic defect grafted with puerarin with calcium sulphate granules versus calcium sulphate granules as a solograft.
Materials and Methods: This was a randomized controlled clinical trial conducted on 20 patients suffering from maxillary cystic lesions with size more than 3 cm2 indicated for enucleation without the need for resection or plate reconstruction.
In the first group (A): Bony cavities were grafted by Puerarin mixed with hemihydrated calcium sulphate bone graft granules, while in the second group (B): The bony cavities were grafted by hemihydrated calcium sulphate bone graft granules only. All patients were followed up for 6 months recording the progress of the healing both clinically and radiographically via CBCT.
Results: Surgeries went uneventful in patients of both groups. No notable complications occurred during the surgical procedures and the healing period of the two groups. Radiographic results after 6 months showed that there was a significant decrease in cyst volume in the purerein group compared to the other group.
Conclusions: Puerarin is a promising graft material with probably an osteoinductive role, an issue that needs more researches to optimize its use and to understand its bone forming mechanism.

Keywords

Egyptian Dental Journal
Volume 67, Issue 2 - Serial Number 2
April (Oral Surgery)
April 2021
Pages 1147-1156

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