The antimicrobial effect of eugenol on lactobacilli isolated from children’s saliva compared to chlorhexidine (in-vitro study)

Document Type : Original Article

Authors

1 Department of Pediatric Dentistry, Faculty of Dentistry, Pharos University in Alexandria, Alexandria, Egypt.

2 Senior Student, Faculty of Dentistry, Pharos University in Alexandria, Alexandria, Egypt.

3 Department of Microbiology, Faculty of Dentistry, Pharos University in Alexandria, Alexandria, Egypt

Abstract

Background: Eugenol is a frequent component of dental biomaterials and is known to exhibit a range of antimicrobial activity. However, there is a lack of reports on evaluating the antimicrobial activity of eugenol versus chlorhexidine on oral lactobacilli. Material and methods: In the current study, we evaluated the in vitro antimicrobial activity of eugenol by agar diffusion method on 15 Lactobacillus isolates initially isolated from pre-school children and compared the efficacy of eugenol with chlorhexidine. Results: the study showed inhibition zones of eugenol ranged from 6 to 10 mm, while those of chlorhexidine ranged from 7 to 11mm. The statistical analysis using paired t-test revealed a significant difference (P < 0.001) for eugenol and chlorhexidine groups with respect to their antimicrobial efficacy against oral lactobacilli. The minimum inhibitory concentration of eugenol and chlorhexidine were 100-400 and 20-40 micro gm/ml, respectively. Conclusion: The effectiveness of eugenol against lactobacilli was promising in inhibiting caries

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Egyptian Dental Journal
Volume 68, Issue 2 - Serial Number 1
April (Orthodontics, Pediatric & Preventive Dentistry)
April 2022
Pages 1141-1148

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