COMPARATIVE EVALUATION OF OZONE GAS AND OZONATED WATER AFTER ARTHROCENTESIS IN MANAGEMENT OF TEMPRO MANDIBULAR JOINT INTERNAL DERANGEMENT: A CLINICAL RANDOMIZED CONTROLLED STUDY

Tempro-mandibular joint pathology is a dilemma that concerns with temporo-mandibular disorders, tumors, infections, growth development anomalies, and traumatic lesions. TMDs require a multidisciplinary approach. Usually, first treatment options are noninvasive treatments. Other treatment option was present when conservative (non-invasive) treatment of TMD was failed to obtain the suggested results as TMJ arthrocentesis. There are many different materials that can be injected after TMJ arthrocentesis including non-steroidal anti-inflammatory drugs (NSAIDs), opioid analgesics, corticosteroid, sodium hyaluronate (SH), platelet-rich plasma (PRP) and recently ozone.
AIM: The aim of this study was to compare and evaluate the effect of ozone gas and ozonated water after arthrocentesis in management of temporomandibular joint internal derangement.
PATIENTS AND METHODS:
This was a clinical randomized controlled study conducted on 28 patients suffered TMJ internal derangement (anterior disc displacement with reduction). The patients were randomly divided into 2 groups, each group consists of 14 patients. Group A (Ozone group) received ozone gas injection after arthrocentesis with Ringer's solution. Group B (ozonated water group) received ozonized water arthrocentesis after arthrocentesis with Ringer's solution.
RESULTS:
When comparing the two groups, there were no statistically significant differences; between group A and group B regards changes in measuring pain on visual analogue scale (VAS) from pre-operative till post-operative at 12 months follow up periods (P value= 0.086). While, there were statistically significant differences; between group A and group B regards changes in maximum painless opening from pre-operative till post-operative at 12 months follow up periods (P value= 0.002)