THE EFFICACY OF PROPHYLACTIC INTRALIGAMENTARY INJECTION OF PIROXICAM VERSUS MEPECAINE FOR MANAGEMENT OF POST-ENDODONTIC PAIN IN MANDIBULAR POSTERIOR TEETH WITH IRREVERSIBLE PULPITIS AND APICAL PERIODONTITIS A RANDOMIZED CLINICAL TRIAL (THERAPEUTIC STUDY) (PART 2)

Document Type : Original Article

Authors

1 Master Degree in Endodontics Cairo University

2 Professor of Endodontic Dentistry, Faculty of Oral and Dental Medicine, Cairo University.

3 Associate Professor of Endodontic Dentistry, Faculty of Oral and Dental Medicine, Cairo University

Abstract

Aim: This study aimed to investigate the effect of prophylactic intraligamentary injection of piroxicam versus mepecaine on management of post-endodontic pain after single-visit treatment of mandibular posterior teeth with irreversible pulpitis and apical periodontitis.
Methodology: Twenty patients with symptomatic irreversible pulpitis and apical periodontitis in their mandibular posterior molars were included in the study. post-operative pain experienced after administration of prophylactic intraligamentary piroxicam in the experimental group or prophylactic intraligamentary mepecaine in the control group was evaluated after 6,12,24, and 48 hours using the numerical rating scale (NRS). Demographic data and NRS scores were collected from the patients and statistically analyzed.
Results: Results showed that the prophylactic administration of intraligamentary piroxicam before single-visit root canal treatment had no significant decrease in pain intensity at 6,12,24, and 48 hours postoperatively compared to mepecaine group. The piroxicam group showed no statistically significant decrease in pain on percussion after 7 days. The total number of analgesic tablets taken in the Piroxicam group was not statistically significantly different from the control group postoperatively.
Conclusion: It could be concluded that the prophylactic administration of intraligamentary piroxicam had no better potency in reducing post-endodontic pain than intraligamentary mepecaine for vital teeth with irreversible pulpitis and symptomatic apical periodontitis in mandibular molar teeth during the first 48 hours. Regarding postoperative pain on percussion, intraligamentary piroxicam has the same pain level as the mepecaine group. Participants in the piroxicam group used a comparable number of brufen tablets to the mepecaine group.

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Egyptian Dental Journal
Volume 68, Issue 4 - Serial Number 5
October (Conservative Dentistry and Endodontics)
October 2022
Pages 3937-3960

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