Bone gain in alveolar cleft repair combining Hyaluronic acid with anterior iliac crest corticocancellous graft

Document Type : Original Article

Authors

1 Lecturer of Oral & Maxillofacial Surgery, Oral & Maxillofacial Surgery Department, Faculty of Dentistry, Cairo University, Cairo. Lecturer of Oral & Maxillofacial Surgery, School of Dentistry, New Giza University, Giza,

2 BDS, MSc, Researcher of Oral & Maxillofacial Surgery, Oral & Maxillofacial Surgery Department, Faculty of Dentistry, Cairo University, Cairo

3 Lecturer of Oral & Maxillofacial Surgery, Oral & Maxillofacial Surgery Department, Faculty of Dentistry, Cairo University, Cairo

4 Associate professor, Oral and Maxillofacial Radiology Department, Faculty of Dentistry, Cairo University. Giza, Egypt, Associate professor of Oral and Maxillofacial Radiology, School of Dentistry, New Giza University, Giza

5 Lecturer of Oral and Maxillofacial Surgery, Future University in Egypt

6 Associate professor of Oral & Maxillofacial Surgery, Oral & Maxillofacial Surgery Department, Faculty of Dentistry, Cairo University, Cairo

Abstract

Purpose: This study aims to evaluate the osteogenic effect of adding Hyaluronic acid (HLA) gel to anterior iliac crest corticocancellous graft for secondary alveolar cleft repair. Methods: The study included forty patients with unilateral alveolar cleft scheduled for repair using autogenous bone graft from the iliac crest. The included patients were divided into two groups. HLA group underwent alveolar bone grafting mixed with Hyaluronic acid gel while the control group underwent alveolar bone grafting alone from the iliac crest. CBCT images were obtained at 1 week and at 6 months following the procedure. The gained bone volume and density were assessed and compared between the two groups. Results: At the end of the follow up period, the HLA group showed more bone gain with higher density compared to the control group. Conclusion: The addition of Hyaluronic acid to bone graft showed uneventful healing and showed an osteogenic potential with increased amount of bone gain.

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Egyptian Dental Journal
Volume 69, Issue 4 - Serial Number 2
October Oral Surgery
October 2023
Pages 2619-2625

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