Aim: The purpose of this study is to assess the effect of both low level laser therapy as a photobiomodulation and non-cross linked hyaluronic acid injection for lip hydration. Materials & methods: Twenty female Middle Eastern patients who seeked a lip rejuvenation treatment at our clinic were included in the study. Using 650 nm diode laser, photobiomodulation was applied to the lips for 5 minutes to each lip quadrant followed by injecting non-cross linked hyaluronic acid skin booster using a micro cannula. Patient satisfaction score was recorded through different follow up intervals (immediately after the procedure, 3 weeks & 3 months). Statistical analysis was performed to evaluate the patient satisfaction score through the follow up sessions. Results: Patients in this study reported a market improvement in the lip texture immediately after the procedure with almost minimal swelling. The latter improvement remained persistence up to 3 months. Conclusion: The combined use of low level laser therapy in addition to non-cross linked hyaluronic acid skin booster injections for lip boosting may offer an acceptable results for lip hydration with a minimal swelling post injection. Keywords: Hyaluronic acid skin boosters, photobiomodulation, lip rejuvenation, Diode laser.
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