Comparative Clinical Evaluation of Photodynamic Therapy with or without Vitamin D as an Adjunctive to Non-surgical Periodontal Therapy for Management of Stage II Grade B Periodontitis: A Randomized Controlled Clinical Trial.

Document Type : Original Article

Authors

1 Associate Professor of Oral Diagnosis, oral Medicine and Periodontology, Faculty of Dentistry, Cairo University

2 Lecturer of Oral Diagnosis, oral Medicine and Periodontology, Faculty of Dentistry, MTI University

Abstract

Aim: This study aimed to evaluate the efficacy of Photodynamic Therapy (PDT) alone versus PDT with Vitamin D adjunctive to non-surgical periodontal therapy (NSPT) in treatment stage II Grade B periodontitis.
Subjects, materials and methods: A total of 24 patients (12 patients per group) with a diagnosis of Stage II Grade B periodontitis. The control group: Non- Surgical Periodontal Therapy (NSPT) + Photodynamic Therapy (PDT) alone and the test group: Non- Surgical Periodontal Therapy (SRP) + Photodynamic Therapy (PDT) with Vitamin D were performed. This randomized controlled clinical trial study examined the efficacy of PDT with or without vitamin D as an adjunctive to NSPT by comparing their effects on clinical outcomes (CAL- PI- GI) and radiographic bone loss was taken at baseline for confirming the diagnosis. NSPT was performed for the two groups. PDT was carried out using a blue halogen curing light with a wavelength of 470 nm and an intensity of 620 mW/cm2, running continuously for five minutes. Using an applicator, bottom of the periodontal pocket was treated with 2% methylene blue (the photosensitizer). After five minutes, saline was used to rinse the photosensitizer before it was subjected to a blue halogen curing light day zero. Process was repeated on days seven and twenty-one. Prior to intervention, blood samples were taken from each group to measure serum vitamin D levels.
Conclusion: Considering the restrictions of this randomized controlled clinical trial study, it can be concluded that the PDT and Vitamin D supplements gave the best clinical results.

Keywords

Main Subjects

Egyptian Dental Journal
Volume 71, Issue 3 - Serial Number 3
July (Oral Medicine, X-Ray, Oral Biology & Oral Pathology)
July 2025
Pages 2155-2165

Files

Share

How to cite

Statistics