Clinical and Radiographic Effect of Extracted Autogenous Demineralized Dentin as a Bone Graft Substitute in Management of Periodontal Intrabony Defects: A Case Series

Document Type : Original Article

Authors

1 Oral Medicine and Periodontology Department, Faculty of Dentistry, Cairo University, Egypt. Periodontology Department, School of Dentistry, Newgiza University, Egypt

2 Oral Medicine and Periodontology Department, Faculty of Dentistry, Cairo University, Egypt.

Abstract

Aim: The study aimed to assess the effectiveness of using an autogenous demineralized dentin graft (ADDG) as a bone substitute with modified minimally invasive surgical technique (M-MIST) in improving the radiographic and clinical outcomes of intra-bony defects.
Methods: Ten periodontitis patients diagnosed as Stage III, Grade B were enrolled in the trial, with 2 or 3 walled intra-bony defects, probing depth (PD) ≥ 6 mm and intra-osseous defect depth ≥ 3mm and having unrestored or supernumerary tooth that needed extraction were treated with M-MIST and ADDG after receiving steps 1 and 2 periodontal therapies. Clinical parameters as clinical attachment level gain (CAL) (primary outcome), gingival margin level (GML) and probing depth (PD) were measured at baseline then after three and six months, while radiographic parameters as radiographic linear defect depth (RLDD) change, radiographic bone fill (RBF) and radiographic bone density (RBD) were measured at baseline and after six months.
Results: There was a statistically significant gain in CAL, reduction in PD and GML after 3 months. These measurements then showed no statistically significant change from three to six months. Additionally, there was a significant decrease in RLDD and a measurable increase in bone density after six months.
Conclusion: M-MIST and ADDG exhibited major improvements in radiographic and clinical parameters 6 months post-operative. This suggests the potential use of ADDG instead of conventional types of bone grafting materials in management of the intra-bony defects of periodontitis patients.

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Egyptian Dental Journal
Volume 71, Issue 4 - Serial Number 3
(Oral Medicine, X-Ray, Oral Biology & Oral Pathology)
October 2025
Pages 3137-3149

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