Evaluation of Antimicrobial Effect of Nano Based Intracanal Medication Based on Magnesium oxide and Conventional Calcium Hydroxide against Enterococcus Faecalis (An In-Vitro study)

Document Type : Original Article

Authors

1 MSc Student, Endodontic Department, Minia University, Egypt

2 Assistant Professor, Microbiology & Immunology Department, Faculty of Pharmacy, Minia University, Egypt Microbiology and Immunology Department, Faculty of Pharmacy, Deraya University, Minia, Egypt.

3 Assistant Professor, Department of Endodontics, Faculty of Dentistry, Minia University, El-Minia, Egypt

4 Microbiology and Immunology , University of Deraya , Minia , Egypt

Abstract

Aim: evaluate the antibacterial effect of nano based intracanal medicaments Magnesium Oxide Nanoparticles (nMgO) comparing to conventional Calcium hydroxide.
Materials and methods: 80 human uni-radicular teeth were decorated then instrumented using Protaper universal Rotary File System till file (F4). After being infected with E. faecalis the samples were allocated into four equal experimental groups at random based on the type of intracanal medicament used. The roots were cultured for 21 days after being arranged vertically in sterilized glass tubes. Using Paper points Size 40, shaved dentin chips were gathered for bacterial culture. In order to measure the antibacterial activity, bacterial colony-forming units per milliliter (CFUs/ml) were used.

Results: The highest count was found in the control group, followed by nMgO, then the Calcium hydroxide group, while the lowest count was found in calcium hydroxide+ nMgO group.

Conclusion: The combination was the most effective in suppressing the bacterial load of E. faecalis, after a 21-days incubation period.

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Egyptian Dental Journal
Volume 71, Issue 4 - Serial Number 5
Conservative Dentistry and Endodontics
October 2025
Pages 3423-3431

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