Remineralisation Effect of Nano-Hydroxyapatite and Fluoride Containing Toothpastes on Artificial Enamel Caries (An In vitro Study)

Document Type : Original Article

Authors

1 Demonstrator of operative Dentistry, Faculty of Dentistry, Assuit University.

2 Associate Professor of conservative Dentistry, Faculty of Dentistry, Minia University

Abstract

Aim: This investigation was carried out to assess and evaluate the reminiralization ability of artificial enamel carious lesions by (n-HAP) tooth paste in comparison with (F) tooth paste. Material and Methods: 60 healthy extracted teeth the roots were cut and sectioning crowns. The samples were placed in acrylic resin blocks, covered with nail varnish except a 3x3 mm of exposed enamel. The samples were divided into three groups based on the toothpaste used G A1 (n-hap), GA2 (F) and GA3 (n-hap+ F) . The initial enamel lesion was produced using deminiralizing solution. Applying toothpaste for 30 cycles twice daily, and washing them under running water. In pH-cycling models samples were demineralized twice daily for three hours, followed by a two-minute treatment with a remineralizing agent slurry twice daily over a 24-hour cycle. After two weeks and one month of brushing, specimens were examined utilizing (EDAX) and (SEM). Results: At base line and After demineralization, there was no statistically significant difference found between the three tested toothpastes respectively, while after 2 weeks The statistical analysis was G A1 (n-hap) was significantly higher than of GA2 (F) and GA3 (n-hap+ F). After 1 month, there was a statistically significant difference as G A1 (n-hap) was significantly higher than GA2 (F) and GA3 (n-hap+ F). Conclusions: The current investigation found that the three tooth paste were efficient at treating and remineralizing the initial carious lesion. , nano-hydroxyapatite paste had superior mean values in remineralization of demineralized enamel

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Egyptian Dental Journal
Volume 71, Issue 4 - Serial Number 5
Conservative Dentistry and Endodontics
October 2025
Pages 3493-3505

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