EFFECT OF CALCIUM CHANNEL-BLOCKERS ON CLINICAL OUTCOMES OF IMPLANT RETAINED OVERDENTURE IN HYPERTENSIVE PATIENTS

Document Type : Original Article

Authors

1 Lecturer, Prosthodontic Department, Faculty of Dentistry, Tanta University

2 Lecturer, Prosthodontic Department, Faculty of Dentistry, Tanta University.

Abstract

Purpose: Calcium channel-blocking agents are used extensively for the management of hypertension. Gingival overgrowth around natural teeth has been previously reported in the literature with patients taking calcium channel-blocking agents. There are limited scientific documentations illustrating its effects around dental implants. This study compared the effects of Calcium channel-blocking agents (Amlodipine) and angiotensin receptor blockers (Valsartan) on dental implants retaining overdentures in hypertensive patients clinically and radiographically after two years of function.
Materials and Methods: Twenty completely edentulous male hypertensive patients wearing mandibular overdentures retained by two implants (3.6*12mm Dentium Two– piece (Ball type) dental implant, Dentium Implant System, Korea) were included in this study, Patients were equally and randomly divided into two groups, Group (I) were managed by Amlodipine according to their physician to control the hypertension. Group (II) were managed by Valsartan according to their physician to control the hypertension. Each case was evaluated clinically concerning plaque index, gingival index, probing depth and implant stability by using OSSTELL ISQ and radiographically concerning marginal bone loss at baseline (overdenture insertion) and after
6, 12 and 24 months. Data were collected, tabulated and statistically analyzed using t-Student test.
Results: No statistical significant difference was found between the two groups (P≥0.05).
Conclusions:  Based on the limitations of the present study and although no statistical difference was found between the effect of Amlodipine and Valsartan on dental implants under overdentures. Peridontium around implants in hypertensive patients managed by calcium channel blockers Amlodipine was affected more than that managed by Valsartan.

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