Enamel Surface Alterations in Molars of Young Rats of Diabetic Mothers

Document Type : Original Article

Authors

1 Associate Professor, Department of Oral Biology, Faculty of Oral and Dental Medicine, Cairo University, Egypt

2 Associate Professor, Department of Oral Biology, Faculty of Oral and Dental Medicine, Suez Canal University, Egypt

Abstract

Objective: Enamel defects are remarkable problems frequently observed in offspring of diabetic women. So, the goal of the current work was determination of enamel surface alterations in molars of young rats born to diabetic mothers.
Material and Methods: 16 heathy adult female albino rats were equally divided into two groups. Induction of diabetes was done in one group by alloxan and the other group act as control group. Four adult male rats were used for fertilization of both groups. All off springs were sacrificed with an overdose of ether at 6 weeks after birth. SEM examination of the occlusal surfaces of the mandibular first molar teeth was done using environmental scanning electron microscope. Teeth were examined for chemical characterization using Electron Dispersive Analytical X-ray (EDAX).
Results: Enamel revealed multiple ultrastructural alterations in diabetic group. By EDAX examination, there was a decrease in the content of calcium and phosphorous in diabetic group as compared with control, altering the calcium to phosphorus ratio.
Conclusion: Maternal diabetes had a detrimental influence on the function of ameloblasts in laying down enamel inducing defective enamel.

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