Effects of Moringa Oleifera Aqueous Leaf Extract on Submandibular Salivary Glands of Diabetic Albino Rats

Document Type : Original Article

Authors

1 Lecturer of Oral Histology, Faculty of Oral and Dental Medicine, Future University in Egypt

2 Lecturer of Oral Pathology, Faculty of Oral and Dental Medicine, Future University in Egypt

3 Lecturer of Microbiology, General Science Department, Faculty of Oral and Dental Medicine, Future University in Egypt

Abstract

Moringa Oleifera (MO), also known as the ‘drumstick tree,’ is recognized as a nutritious and cheap source of phytochemicals, that a have a prominent anti-oxidative effect. Salivary gland dysfunction has been frequently reported in diabetic patients. Diabetes is a chronic metabolic disease that has complications mainly resulting from persistent hyperglycemia.
Aim of the study: To Assess the effect of MO aqueous leaf extract on blood glucose levels in diabetic albino rats and its effect on submandibular salivary glands of diabetic albino rats.
Materials and methods: the study comprised three groups; control, diabetic and MO treated groups. The experiment was terminated after fourteen days. The evaluation was performed by measuring the blood glucose levels and weight. Histological evaluation was done by H&E, PAS and IHC for COX-2.
Results: the blood glucose levels and histological signs of diabetic complications were significantly lowered in the MO treated group.
Conclusion: MO is a promising anti-diabetic treatment and may even reverse some of the diabetic complications.

Keywords

Files

Share

How to cite

Statistics