EFFECT OF TISSUE CONDITIONER COMBINED WITH NYSTATIN ON GROWTH OF CANDIDA ALBICANS IN COMPLETE DENTURE WEARERS

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Researcher in Fixed and Removable Prosthodontic Department, National Research Centre, Cairo, Egypt

Abstract

Aim: this study aimed to evaluate the effect of incorporation of Nystatin antifungal with tissue conditioner applied to the maxillary complete denture on growth of Candida Albicans.
Materials and methods: Fifteen completely edentulous patients were selected and conventional complete dentures were fabricated for each patient. Viscogel tissue conditioner was applied at denture delivery. Isolation and identification of Candida albicans were done using Agar core inhibition assay after two months from wearing the denture. Then, a new application of viscogel mixed with Nystatin antifungal was applied replacing the first one and after additional two months from wearing the denture, Isolation and identification of Candida albicans was done.
Results: there was no significant difference was observed before and after application of Nystatin antifungal.
Conclusion: tissue conditioner when mixed with Nystatin antifungal showed no marked effect on inhibition of Candida Albicans.

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